1. Intaxication: Euphoria at getting a tax refund, which lasts until you realize it was your money to start with.
2. Reintarnation: Coming back to life as a hillbilly.
3. Bozone (n.): The substance surrounding a stupid person that stops bright ideas from penetrating. The bozone layer, unfortunately, shows little sign of breaking down in the near future.
4. Foreploy: Any misrepresentation about yourself for the purpose of getting laid.
5. Cashtration (n.): The act of buying a house, which renders the subject financially impotent for an indefinite period.
6. Giraffiti: Vandalism spray-painted very, very high.
7. Sarchasm: The gulf between the author of sarcastic wit and the person who doesn't get it.
8. Inoculatte: To take coffee intravenously when you are running late.
9. Hipatitis: Terminal coolness.
10. Osteopornosis: A degenerate disease. (This one got extra credit.)
11. Karmageddon: It's like, when everybody is sending off all these really bad vibes, right? And then, like, the Earth explodes and it's like, a serious bummer.
12. Decafalon (n.): The grueling event of getting through the day consuming only things that are good for you.
13. Glibido: All talk and no action.
14. Dopeler effect: The tendency of stupid Ideas to seem smarter when they come at you rapidly.
15. Arachnoleptic fit (n.): The frantic dance performed just after you've accidentally walked through a spider web.
16. Beelzebug (n.): Satan in the form of a mosquito, that gets into your bedroom at three in the morning and cannot be cast out.
17. Caterpallor (n.): The colour you turn after finding half a worm in the fruit you're eating.
18. Testiculate (v.): To wave your arms around while talking bollocks.
And the pick of the literature:
19. Ignoranus: A person who's both stupid and an asshole
I can't think of any witty ones to add to this - but I expect that my friends can (please):